JADIKAN KAMI TUNAS-TUNAS BANGSA YANG BERILMU TINGGI

Rabu, 26 Maret 2008

TUJUAN PENDIDIKAN


  1. Tujuan Pendidikan Tingkat Satuan Pendidikan

Tujuan pendidikan tingkat satu pendidikan dasar dan menengah dirumuskan mengacu kepada tujuan umum pendidikan berikut :

  1. Tujuan pendidikan dasar adalah meletakkan dasar kecerdasan pengetahuan, kepribadian, akhlak mulia, serta ketrampilan untuk hidup mandiri dan mengikuti pendidikan lebih lanjut.

  2. Tujuan pendidikan menengah adalah meningkatkan kecerdasan, pengetahuan, kepribadian, akhlak mulaia, serta ketrampilan untuk hidup mandiri dan mengikuti pendidikan lebih lanjut.

  3. Tujuan pendidikan menengah keguruan adalah meningkatkan kecerdasan pengetahuan kepribadian, akhlak mulia, serta ketrampilan untuk hidup mandiri dan mengikuti pendidikan lebih lajut sesuai dengan kejuruannya.


  1. Struktur dan Muatan Kurikulum Tingkat Satu Pendidikan

Struktur dan muatan KTSP pada jenjang pendidikan dasar dan menengah yang tertuang dalam S1 meliputi lima kelompok mata pelajaran sebagai berikut :

  1. Kelompok mata pelajaran agama dan akhlak mulia

  2. Kelompok mata pelajaran kewarganegaraan dan kepribadian

  3. Kelompok mata pelajaran ilmu pengetahuan dan teknologi

  4. Kelompok mata pelajaran estetika

  5. Kelompok mata pelajaran jasmani dan olahraga kesehatan

Kelompok mata pelajaran tersebut dilaksanakan melalui muatan atau kegiatan pembelajaran sebagaimana diuaikan dalam PP 19 tahun 2005 pasal 7.







TUJUAN KURIKULUM


Kurikulum adalah seperangkat rencana dan pengaturan mengenai tujuan, isi dan bahkan pelajaran serta cara yang digunakan untuk mencapai tujuan pendidikan tertentu.

Tujuan atau panduan penyusunan KTSP ini untuk menjadi acuan bagi satuan pendidikan SD/MI/SDLB, SMP/MTs/SMPLB, SMA/MA/SMALB dan SMK/MAK dalam penyusunan dan pengembangan kurikulum yang akan dilaksanakan pada tingkat satuan pendidikan yang bersangkutan.

Kurikulum tingkat satuan pendidikan (KTSP) adlaah kurikulum operasional yang disusun oleh dan dilaksanakan dimasing-masing satuan pendidikan. KTSP terdiri dari tujuan pendidikan tingkat satuan pendidikan, struktur dan muatan kurikulum tingkat satuan pendidikan, kelender pendidikan dan silabus.

KTSP disusun dengan memperhatikan hal-hal sebagai berikut :

    1. Peningkatan iman dan takwa serta akhlak mulia

    2. Peningkatan potensi, kecerdasan, dan minat sesuai dengan tingkat perkembangan dan kemampuan serta didik.

    3. Keragaman potensi dan karakteristik daerah dan lingkungan

    4. Tuntutan pembangunan daerah dan nasional

    5. Tuntutan dunia kerja

    6. Perkembangan ilmu pengetahuan, teknologi dan seni

    7. Agama

    8. Dinamika perkembangan global

    9. Persatuan nasional dan nilai-nilai kebangsaan

    10. Kondisi sosial budaya masyarakat setempat

    11. Kesetaraan jender

    12. Karakteristik satuan pendidikan




TUJUAN LEMBAGA KOMPETENSI (KELULUSAN)


Kenaikan kelas dilaksanakan pada setiap akhir tahun ajara. Kriteria kenaikan kelas diatur oleh masing-masing direktorat teknis terkait.

Sesuai dengan ketentuan PP 19 tahun 2005 pasal 72 ayat (1), perserta didik dinyatakan lulus dari satuan pendidikan pada pendidikan dan menengah setelah :

  1. Menyelesaikan seluruh program pembelajran

  2. Memperoleh nilai minimal baik pada penilaian akhir dan seluruh mata pelajaran kelompok, mata pelajaran agama dan akhlak mulia, kelompok kewarganegaraan dan kepribadian, kelompok mata pelajaran estetika, dan kelompok mata pelajaran jasmani, olahraga dan kesehatan.

  3. Lulus ujian sekolah atau madrasah untuk kelompok mata pelajaran ilmu pengetahuan dan teknologi, dan

  4. Lulus ujian nasional

















PENGEMBANGAN KURIKULUM

DAN SILABUS

DOSEN : Drs. I.B. KT. Perdata, M.Pd
















NAMA : NI PUTU BUVIA PURMAYANTI

NO : 46/2156/AM.W/08

ANGKATAN : 41/2008



  1. PENDAHULUAN

I.1 Latar Belakang

Sel bakteri amat beragam panjangnya, sel beberapa spesies dapat berukuran 100 kali lebih panjang daripada sel spesies yang lain. (Pelczar. 2006). Walaupun ada ratusan spesies bakteri yang berbeda, namun suatu bakteri dalam bentuk sel tunggal akan memiliki salah satu dari tiga bentuk yang umum dikenal. (Ramona, dkk. 2007). Berdasarkan bentuk morfologinya maka bakteri dapat dibagi atas tiga golongan yaitu :

  1. Bentul bulat/elips/spherical shape yang lazim disebut dengan coccus.

  2. Bentuk batang yang umum dikenal basil

  3. Bentuk spiral.

Individu-individu sel dari spesies yang berbeda-beda menunjukkan perbedaan-perbedaan yang mencolok dalam hal panjang, jumlah dan amplitude spiralnya serta kekakuan dinding selnya. (Pelczar. 2006). Bentuk tubuh bakteri terpengaruh oleh keadaan medium dan oleh usia.

Maka untuk membandingkan bentuk serta besar sama, penyinaran oleh sumber cahaya apapun, penyinaran oleh sumber cahaya apapun harus sama, dan usia piaraan pun harus sama (Dwidjoseputro, 2003).

Variasi bakteri berbentuk bulat atau coccus biasanya dipakai sebagai ciri yang khas dalam proses identifikasi (Ramona, dkk. 2006).

Beberapa variasi bentuk tersebut antara lain :

  1. Diplococcus : Dua buah sel yang saling berpasangan

Contoh : Streptococcus pneumoniae.

  1. Streptococcus : Untaian sel yang lebih, dari 4 sel dan membentuk suatu untaian yang menyerupai rantai

Contoh : Streptococcus pyogenes.

  1. Tetracoccus : Empat buah sel yang saling berdempetan yang membentuk suatu bentuk yang menyerupai bujur sangkar

Contoh : Pediococcus cerevisiae



  1. Staphylococcus : Kumpulan sel yang saling berdempetan membentuk gerombol dan bercabang

Contoh : Staphylococcus aureus.

  1. Sarcina : Kelompok yang terdiri atas delapan sel (empat sel di bagian depan dan 4 sel di bagian belakang

Contoh : Sarcinia Ventricullin.

Beberapa dengan bakteri berbentuk bulat, bakteri bentuk batang (basil) jarang sekali dalam variasi diatas, jika dialam dijumpai variasi bakteri berbentuk batang (basil), maka hal tersebut cenderung disebabkan oleh tahap pertumbuhannya atau kondisi-kondisi yang mempengaruhi kultur tersebut. Sedangkan bakteri bentuk spiral pada umumya dijumpai dalam bentuk soliter atau bersel tunggal dan bukan merupakan kumpulan sel yang berdempetan. (Ramona, dkk. 2006).

Pemeriksaan dengan EM (electron mikroskop) menunjukkan adanya struktur-struktur diluar dinding sel dan struktur lain yang terbungkusnya didalam dinding sel. Struktur di luar dinding sel (Kawuri. 2007) antara lain :

Flagellum mempunyai ukuran panjang 1-70 mikron dan tebal 12-15 millimikron. Umumnya bakteri bakteri berbentuk batang mempunyai flagel (Entjang. 2003). Flagellum terdiri dari 3 bagian yaitu tubuh dasar, struktur kait dan sehelai filamen diluar dinding sel. Untuk melihat flagella preparat harus diberi pewarnaan leifson atau pewarnaan negarif (Kawuri. 2007).

Berdasarkan jumlahnya dan letaknya flagella dibedakan menjadi :

  1. Monotrichous bakterium : Bakteri yang memiliki flagella tungal di ujung selnya.

  2. Liphotrichous : Organism : Memiliki 2 atau lebih flagella pada salah satu kutub selnya.

  3. Amphitrichous bakterium : Memiliki sejumlah flagella pada kedua ujungnya.

  4. Peritrichous organism : Organisme yang ditutupi oleh flagella (Alcamo. 1997).

Struktur yang terletak di dalam dinding sel antara lain : membran sitoplasma, dan spora (Alcamo. 1997).


I.2 Rumusan Masalah

  • Bagaimana bentuk-bentuk dari berbagai jenis sel bakteri?

  • Bagaimanakah variasi bentuk dari asosiasi sel-sel bakteri?


I.3 Tujuan

  • Untuk mengetahui bentuk-bentuk dari berbagai sel bakteri

  • Untuk mengetahui variasi bentuk dari asosiasi sel-sel bakteri

  1. MATERI DAN METODE

II.1 Alat dan Bahan

  1. Mikroskop cahaya

  2. Objek glass dan alat fiksasi

  3. Minyak emersi

  4. Freparat awetan bakteri

  5. Xylol


II.2 Cara Kerja

  1. Diamati bentuk-bentuk bakteri dengan menggunakan mikroskop cahaya dan dimulai dengan pembesaran lemah

  2. Bila pengamatan kurang jelas, dilakukan pengamatan dengan lensa objektif yang berkekuatan 100x (sebelum diamati, diatas preparat ditetesi dengan minyak emersi pada pembesaran 100x).

  3. Bentuk-bentuk bakteri dan variasinya digambar

  4. Minyak emersi yang melekat pada lensa dibersihkan dengan xylol.





  1. HASIL DAN PEMBAHASAN

III.1 Hasil

(terlampir)


III.2 Pembahasan

Pada praktikum ini dilakukan pengamatan bentuk-bentuk bakteri dengan menggunakan preparat dari bakteri Vibrio chollerae, Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, Spirochaeta, Streptococcus pyogenes, Streptococcus faecalis. Pengamatan menggunakan mikroskop cahaya dimulai dengan pembesaran lemah, namun sel bakteri kurang jelas dapat diamati, kemudian pembesaran ditingkatkan lagi menjadi 100 x 10 sehingga semua jenis bakteri bisa dilihat dengan jelas. Pada saat melihat sel bakteri di bawah mikroskop cahaya dengan menggunakan pembesaran 100 x 10, preparat harus dioleskan dengan minyak emersi. Hal ini dikarenakan untuk menghindari pelecetan antara kaca preparat dan lensa objektif akibat pergesekan satu sama lain dan juga bisa memaksimalkan arah cahaya dan lensa objektif (Prescott, dkk. 1993). Sehingga gambar sel bakteri bisa terlihat jelas dan fokus. Setelah selesai melakukan pengamatan minyak emersi pada lensa harus dibersihkan dengan larutan xylol.

Suatu bakteri dalam bentuk sel tunggal akan memiliki tiga bentuk yang umum yaitu : bentuk coccus, basil, dan spiral. Berikut di bawah ini hasil dari preparat yang telah diamati :

  • Pertama dilakukan pengamatan bekteri Vibrio chollerae. Sifat bekteri bentuk Vibrio, gram negatif, dapat bergerat dengan satu flagel kutub dan tidak mampu berbentuk spora (Endjang, 2003). Hasil dari pengamatan kami didapat bentuk Vibrio chollerae adalah coccus dan bacillus yang berwarna bening. Berdasarkan pengamatan terdapat dua buah sel yang saling berpasangan (diplococcus dan diplobacilus). Berdasarkan literatur Vibrio chollerae berbentuk koma, batang bengkok, bakteri ini sangat aktif bergerak dengan memakai satu flagel kutub (Jawetz, dkk. 1996). Bila dibandingkan dengan hasil pengamatan dengan yangn berdasarkan literatur ternyata tidak terdapat kesamaan bentuk, ini menunjukkan bahwa di dalam preparat yang kami amati tidak terdapat bakteri Vibrio chollerae.Hal ini disebabkan kemungkinan pada saat proses pengkulturan ( pembiakan ) bakteri Vibrio chollerae yang tidak berhasil, ini dikarenakan Vibrio chollerae tidak dapat dikulturkan dalam media dilaboratorium sehingga yang tumbuh dalam media yang disediakan bukanlah Vibrio chollerae melainkan bakteri lain.Bakteri lain yang mungkin diamati oleh praktikan adalah dari jenis diplococcus,coccus dan diplobacillus.

  • Pada pengamatan preparat Eschecriachia coli didapatkan sel bakteri berbentuk bacillus atau batang dengan warna cokelat kemerahan. Pada preparat ini se-sel tunggal dari bakteri ini tersebar dan juga dapat membentuk koloni yang bentuknya tidak beraturan (Prescott,dkk,1996). Kadang kala juga sel bakteri ini jika dilihat di bawah mikroskop kita akan melihat bahwa sel-sel tersebut dalam keadaan yang saling bertumpukan (Pelczar, dkk. 1992). Hal ini dikarenakan bakteri ini bisa membentuk suatu masa yang gelap dan juga dapat melakukan fermentasi laktosa dan fermentasi glukosa serta menghasilkan gas.

  • Pada pengamatan preparat Staphylococcus aureus, didapatkan pengamatan bakteri ini berbentuk coccus yang bergerombol seperti buah anggur dengan warna ungu gelap. Penataan sel-sel bakteri yang sedemikian rupa yangterjadi karena pembelahan sel-selnya terjadi secara acak (random) atau tidak beraturan dan menghasilkan bentuk anggur.(Alcamo, 1997). Kebanyakan bakteri ini membentuk kelompok atau koloni teratur yang terdiri atas empat atau delapan coccus (Jawetz, dkk. 1996).

  • Pada pengamatan preparat Klebsiella pneumonia didapat berdasarkan sel-sel bakteri berbentuk coccus dengan bentuk yang bervariasi dalam penataanya seperti rantai bercabang, bergerombol, serta soliter. Berdasarkan literatur bentuk dari Klebsiella pneumonia adalah berbentuk basilus dan memiliki pili di sekeliling tubuhnya, pili inidigunakan untuk berikaan dwengan jaringan tubuh inangnya (Alcamo. 1997). Hal ini disebabkan karena kesalahan pengamatan dan adanya bakteri lain yang mengkontaminasi preparat ini.

  • Pada pengamatan preparat Spirochaeta duttoni didapatkan berdasarkan pengamatan sel bakteri ini berbentuk spiral dengan menampakkan beberapa sel darah merah yang berasal dari darah manusia. Berdasarkan studi pustaka, filum Spirochaeta duttoni dibedakan menjadi beberapa yaitu Borrelia duttoni yang memiliki bentuk heliks atau berpilin, panjang dan fleksibel. Spesies ini hidup sebagai patogen dan menyebabkan penyakit lyme (Prescott,dkk.1996).Adanya sejumlah bakteri yang tampak disekeliling bakteri ini dikarenakan preparat ini diambil dari darah manusia yang terinfeksi oleh bakteri jenis ini.

  • Pada pengamatan preparat Streptococcus pyogenes dan Streptococcus faecalis didapat berdasarkan pengamatan kami sel bakteri ini berbentuk coccus yang berwarna bening serta menyerupai untaian rantai, terbentuknya variasi bentuk rantai ini terjadi akibat pembelahan sel bakteri kesatu arah bidang pembelahan (Alcamo.1 997). Namun ketika mengamati preparat Streptococcus pyogenes tidak dapat terlihat dengan jelas meskipun sudah menggunakan pembesaran 100 x 10. Hal ini disebabkan karena preparat yang digunakan pada saat praktikum adalah preparat yang usianya sudah agak lama, sehingga preparat akan sedikit buram.

Menurut Ramona ,dkk (1997) bila dijumpai adanya variasi dari bentuk basil maka hal tersebut cenderung disebabkan oleh tahap pertumbuhan atau kondisi-kondisi yang mempengaruhi kultur tersebut.


  1. KESIMPULAN

Berdasarkan pengamatan yang kami lakukan dapat disimpulkan yaitu :

  1. Berdasarkan bentuk morfologinya maka bakteri dapat dibagi atas tiga golongan yaitu :

a.Bentul bulat/elips/spherical shape yang lazim disebut dengan coccus.

b.Bentuk batang yang umum dikenal basil

c.Bentuk spiral.

2.Terdapat variasi bentuk pada bakteri, dimana variasi bentuk ini dapat digunakan dalam proses pengidentifikasian jenis. Bakteri bentuk bulat mengalami modifikasi antara lain bentuk : Monococcus, Diplococcus, Streptococcus, Sarcina, dan Staphylococcus. Bakteri bentuk basil mengalami modifikasi antara lain bentuk : Basil tunggal, Diplobasil, dan Streptobasil. Bakteri bentuk spiral juga mengalami modifikasi antara lain bentuk : Spiral, Vibrio dan Spiroseta.

3.Adanya asssosiasi sel-sel bakteri bentuk coccus terjadi karena arah bidang pembelahan yang berbeda-beda yaitu :

  • Pembelahan pada satu bidang ( diplococcus dan streptococcus)

  • Pembelahan pada dua bidang (tetracoccus)

  • Pembelahan pada tiga bidang (sarcina)

  • Pembelahan pada tiga bidang yang tidak beraturan (staphylococcus)


V. DAFTAR PUSTAKA


Alcamo, I. Edward. 1996. Fundamentals of Microbiology, Fifth Edition. Addison Wesley Longman, Inc. New York.

Pelczar, Michael J.; E.C.S Chan; Noel R. Krieg.1992. Microbiology Concepts and Applications. McGraw-Hill, Inc. New York.


Prescott, Lansing M.; John P. Harley; Donald A. Klein. 1993. Microbiology, Second Edition. WMC Brown Publishers. USA.


Ramona, Yan; Retno Kawuri ; Dharmayasa. 2007. Diktat Kuliah. Mikrobiologi Jurusan Farmasi. Fakultas MIPA, Universitas Udayana. Jimbaran.


Ramona, Yan; Retno Kawuri ; Dharmayasa. 2007. Penuntun Praktikum Mikrobiologi Jurusan Farmasi. Fakultas MIPA, Universitas Udayana. Jimbaran.


Volk, Weasley A.; Wheeler, Margaret F. 1993. Mikrobiologi Dasar. Erlangga. Jakarta.


Entjang,Indan. 2003 . Mikrobiologi dan Parasitologi untuk akademi keperawatan dan sekolah tenaga kesehatan yang sederajat. PT. Citra Aditya Bakti : Bandung.


Dwidjoseputro.2003.Dasar-dasar Mikrobiologi. Djambatan : Malang.


Jawetz,Ernest, dkk. 1996. Mikrobiologi Kedokteran., edisi 20.EGC : Jakarta

BAB I

PENDAHULUAN


1.1 Latar Belakang

Jumlah penduduk yang semakin meningkat menyebabkan timbulnya berbagai masalah lingkungan. demikian pula dengan meningkatnya volume sampah yang akan meningkat menimbulkan degradasi terhadap lingkungan apabila tidak ditangani dengan baik dan benar. degradasi lingkungan merupakan kerusakan-kerusakan dari lingkungan yang dapat menyebabkan penurunan kualitas dari lingkungan tersebut.

pencemaran lingkungan merupakan masalah kita bersama, yang penting untuk diselesaikan, karena menyangkut kesehatan, dan kehidupan kita. siapapun bisa berperan serta dalam menyelsaikan masalah pencemaran llingkungan ini, termasuk kita. dimulai dari lingkungan yang terkecil, diri kita sendiri, sampai lingkungan yang lebih luas (Tiwon, dkk.2002)

Sampah dan pengelolaannnya kini menjadi masalah yang kian mendesak di kota-kota di Indonesia, sebab apabila tidak dilakukan penangan yang baik akan mengakubatkan terjkadinya perubahan keseimbangan lingkungan yang merugikan atau tidak diharapkan sehingga dapat mencemari lingkungan baik terhadap tanah, air dan udara. oleh karena itu untuk mengatasi masalah pencemaran tersebut diperlukan penganan dan pengendalian terhadap sampah. penangan dan pengendalian akan menjadi semakin kompleks dan rumit dengan semakin kompleknya jenis maupun komposisi dari sampah sejalan dengan semakin majunya kebudayaan dan tentunnya disebabkan oleh semakin bertambahnya jumlah penduduk terutama penduduk kota. oleh karena itu penangan sampah di desa-desa (Tiwon,dkk.2003).

Dengan latar belakang inilah kami tertarik untuk mengetahui seberapa besar kerusakan atau degradasi lingkunngan yang diakibatkan oleh pertambahan jumlah penduduk dan peningkatan volume sampah serta proses-proses yang dapat dilakukan untuk mencegah kerusakan tersebut.


1.2 Rumusan masalah

Adapun permasalahan yang dapat dirumuskan disini adalah seberapa besarkah kedegradasi lingkungan yang diakibatkan oleh bertambahnya jumlah penduduk dan meningkatnya volume sampah serta proses-proses apa yang dilakukan untuk mencegah krusakan tersebut.


1.3 Tujuan masalah

Tujuan yang inngin dicapai dengan penulisan ini adalah untuk dapat mengetahui pengaruh pertambahan penduduk dan peningkatan volume sampah terhadap lingkungan serta mengetahui proses-proses yang dapat dilakukan untuk dapat mengatasi akibat buruk yang ditimbulkannya.


1.4 Metode Penulisan

Metode penulisan yang saya gunakan dalam penulisan ini adalah metode kepustakaan yaitu dengan menggunakan beberapa buku acuan dan artikel-ertikel dari internet.














BAB II

PEMBAHASAN


2.1 Digradasi Lingkungan akibat pertambahan penduduk

Manusia memiliki sifat yang tidak pernah puas, dan mereka akan berusaha untuk selalu dapat memenuhi kebutuhannya tersebut. untuk memenuhi kebutuhan tersebut tidak jarang mereka dengan sengaja ataupun tidak sengaja merusak lingkungan.

Salah satu kebutuhan primer manusia yang harus dipenuhi adalah kebutuhan akan papan, yaitu tempat tinggal. Dengan bertambahnya jumlah penduduk tentunya semakin banyak lahan yang dialih fungsikan menjadi perumahan. akibat yang ditimbulkan adalah semakin banyaknya terjadi penebangan pohon, dengan tidak adanya pohon yang diketahui sebagai sumber O2 maka kadar O2 di bumi ini otomatis akan berkurang, disamping pohon juga mampu menahan tanah sehingga tidak terjadi erosi dan pohon mampu menyerap air saat hujan sehingga dapat mencegah terjadinya banjir. Di daerah perkotaan banyak masyarakat yang menggunakan kaca sebagai dinding luar bangunan yang menyebabkan terjadinya efek rumah kaca serta efek dari kebisingan tidak dapat diserap melainkan dipantulkan, disamping itu ada beberapa alat pendingin yang menbimbulkan lapisan ozon dan mampu memicu terjadinya pemanasan global (Nashori, 1997).

Masalah lingkungan lain yang ditimbulkan dengan meningkatnya jumlah penduduk adalah, penduduk perkotaan dalam aktivitasnya sehari-hari sebagian besar menggunakan kendaraan bermotor yang dapat memicu terjadinya polusi udara. limbah dan sampah rumah tangga yang dihasilkan apabila tidak dibuang pada tempatnya misalnya saja dibuang ke sungai dapat mencemari sungai tersebut dan dapat memicu terjadinya banjir pada saat musim hujan.

2.2 Degradasi Lingkungan akibat peningkatan volume sampah

Sampah adalah suatu yang tidak berguna lagi, dibuang oleh pemiliknya atau pemakai semula. Berdasarkan asalnya sampah padat dapat dibedakan menjadi sampah organic dan sampah anorganik. sampah orgaik terdiri dari bahan-bahan penyusun tumbuhan dan hewan yang diambil dari alam atau yang dihasilkan dari kegiatan pertanian, perikanan, atau yang lain. Sampah ini dengan mudah diuraikan dalam proses alami. Sampah rumah tangga sebagian besar merupakan bahan organic. termasuk sampah organic, misalnya sampah dari dapur, sisa tepung, sayuran, kulit buah, dan daun. sampah anorganik bersal dari sumber daya alam tidak terbaharui seperti mineral dan minyak bumi, atau dari proses industri. beberapa dari bahan ini tidak terdapat di alam seperti plastik dan aluminium. Sebagian zat anorganik secara keseluruhan tidak dapat diuraikan oleh alam, sedangkan sebangian lainnya hanya dapat diuraikan dalam waktu yang sangat lama. Sampah jenis ini pada tingkat rumah tangga, misalnya berupa botol, botol plastik, tas plastik, dan kaleng. sampah-sampah ini berasal dari pemukiman pertanian dan perkebunan, sisa bagunan dan gedung, perdagangan dan perkantoran, industeri, rumah sakit, baterai kering dan akumulator bekas ( anonim,?)

Volume sampah yang meningkat beerakibat buruk terhadap lingkungan cairan rembesan sampah yang masuk ke dalam aliran air dan sungai akan mencemari air. berbagai organisme termasuk ikan dapat mati sehingga beberapa spesies akan lenyap, hal ini mengakibatkan berubahnya ekosistem perairan biologis. Peguraian sampah yang dibuang dalam air akan menghasilkan asam organic dan gas cair organic, seperti metana.

Di samping itu pantai kuta beberapa tahun ini menghadapi sejumlah persoalan lingkungan yang cukup komplek salah satunya adalah adanya sampah kiriman yang menumpuk sepanjang pantai. pada bulan februari 2003, persoalan lingkungan pantai kuta semakin bertambah dengan adanya peristiwa kematian ikan secara masal dimana ikan-ikan yang mati tersebut terdampat disepanjang pantai. Kasus besar kematian ikan lemuru secara masal dan terdampar di pantai kuta juga pernah terjadi pada tahun 1994 juga hanya pernah terjadi di pantai kuta tetapi kejadiannya telah berulang-ulang khususnya disepanjang wilayah pesisir Bali barat yang meliputi kabupaten Jembrana, Tabanan, dan Badung. penyebab dari kematian-kematian ikan ini adalah adanya ledakan fitoplankton beracun yang terjadi di pantai kuta yang didorong oleh peningkatan kandungan nutrient khususnya nitrat.

Dampak lalin yang diakibatkan dari bahan utama yang terkandung dari buangan limbah adalah adanya sedimentasi, pencemaran kimia dan logam berat, eutyrotifikasi dan kekurangan oksigen. Sedimentasi menyebabkan menurunnya produktivitas primer, kerusakan habitat, serta degradasi fungdional ekosistem untuk aktifitas mandi, selam, renang, dan pariwisata. adanya pencemaran kimia dan logam berat menyebabkan keracunan pada tanaman atau organisme perairan. adanya penyuburan kembali atau eutrovikasi biasanya fitoplankton mengalami bloming dan jenis yang ada berubah menjadi jenis yang tidak diinginkan. menurunnya kandungan oksigen dalam perairan dapat menyabkan kematian ikan dan vertebrata dasar dan bila berkapanjangan dapat mengalami populasi ikan.

Dalam lingkungan di darat keberadaan sampah yang tidak ditanggulangi dengan baik juga mampu merusak lingkungan. Sampah-sampah plastic yang tidak dapat terurai secara alami akan menyebabkan menurunnya kesuburan tanah tersebut.

2.3 Proses penanggulangannya

Degradasi lingkungan yang disebabkan oleh peningkatan jumlah penduduk dapat diatasi salah satunya dengan memberikan penyuluhan kepada masyarakat tentang betapa pentingnya menjaga kebersihan lingkungan dan akibat-akibat yang ditimbulkan apabila lingkungan kita tidak bersih.

Di samping itu pemerataan penyebaran penduduk tidak dapat dijadikan suatu solusi, dimana diketahui bahwa masalah lingkungan yang disebabkan oleh meningkatnya jumlah penduduk lebih banyak terjadi pada daerah perkotaan hal ini terjadi karena masyarakat desa ingin mengadu nasibnya dan mencari penghidupan yang lebih baik di kota, sehingga terjadi urbanisasi secara besar-besaran. kota tujuan urbanisasi ini tentunya akan menghadapi berbagai permasalahan lingkungan yang ditimbulkan diantaranya semakin banyak sampah dan limbah rumah tangga yang dihasilkan, semaikn banyak penebangan yang dilakukan untuk perumahan. sehingga dengan perataan jumlah penduduk ini diharapkan memperkecil masalah lingkungan yang dihadapi oleh daerah perkotaan.

Untuk mencegah kerusakan lingkungan yang disebabkan oleh peningkatan volume sampah tentunya dapat dilakukan dengan pengolahan sampah dengan baik dan benar. masalah yang sering muncul dalam penanganan sampah kota adalah masalah biaya operasional yang tinggi dan semakin sulitnya ruang yang pantas untuk pembuangan. sebagai akibat biaya operasional yang tinggi, kebanyakan kota-kota di Indonesia hanya mampu mengumpulkan dan membuang kurang lebih 60% dari seluruh produksi sampahnya. dari 60% ini, sebagian besar ditangani dan dibuang dengan cara yang tidak saniter, boros dan mencemari.

Penanganan modal pengolahan sampah perkotaan secara menyeluruh adalah meliputi penghapusan model TPA pada jangka panjang karena dalam banyak hal pengolahan TPA (tempat pembuangan sampah) masih sangat buruk mulai dari penanganan air sampah sampai penanganan bau yang sangat buruk (tiwon,dkk.2003)

Cara penyelesaian yang ideal dalam penanganan sampah diperkotaan adalah dengan cara membuang sampah sekaligus memanfaatkannya sehingga selain membersihkan lingkungan juga menghasilkan kegunaan baru. hal ini secara ekonomi akan mengurangi biaya penanganannya, disamping itu diperlukan pula peran aktif dari masyarakat untuk ikut membantu dalam menyelesaikan masalah sampah ini.

Untuk mengatasi masalah, dengan meningkatnya volume sampah dapat pula dilakukan dengan penyelenggaraan kampanye secara rutin melalui kegiatan penyuluhan, pelatihan pemanfaatan sampah, informasi melalui media tv, radio, majalah dll. mengenai dampak dari sampah yang tidak terolah, dan penyelenggaraan forum-forum informasi daerah dengan melibatkan masyarakat dan lembaga pemerintah sebagai organisasi yang langsung bersentuhan dengan masyarakat dan adanya suatu penegakan hokum secara mandiri dengan sanksi yanmg berjenjang mulai dari peringatan dan pemungutan kembali sampah yang dibuang, kompensasi pembayaran denda, penayangan di media cetak, hingga penegakan hukum lingkungan bagi pelanggar lingkungan (tiwon,dkk.2003)


BAB III

KESIMPULAN


  1. Sampah adalah suatu yang tidak berguna lagi, dibuang oleh pemiliknya atau pemakai semula. Berdasarkan asalnya sampah padat dapat dibedakan menjadi sampah organic dan sampah anorganik. sampah orgaik terdiri dari bahan-bahan penyusun tumbuhan dan hewan yang diambil dari alam atau yang dihasilkan dari kegiatan pertanian, perikanan, atau yang lain. Sampah ini dengan mudah diuraikan dalam proses alami.

  2. Sampah dan pengelolaannnya kini menjadi masalah yang kian mendesak di kota-kota di Indonesia, sebab apabila tidak dilakukan penangan yang baik akan mengakubatkan terjkadinya perubahan keseimbangan lingkungan yang merugikan atau tidak diharapkan sehingga dapat mencemari lingkungan baik terhadap tanah, air dan udara.

Senin, 24 Maret 2008

Opium


Opium

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A field of opium poppies in Burma
A field of opium poppies in Burma

Opium is a narcotic formed from the latex (i.e. sap) released by lacerating (or "scoring") the immature seed pods of opium poppies (Papaver somniferum). It contains up to 16% morphine, an opiate alkaloid, which is most frequently processed chemically to produce heroin for the illegal drug trade. The resin also includes codeine and non-narcotic alkaloids, such as papaverine and noscapine. Meconium historically referred to related, weaker preparations made from other parts of the poppy or different species of poppies. Modern opium production is the culmination of millennia of production, in which the source poppy, methods of extraction and processing, and methods of consumption have become increasingly potent.

Cultivation of opium poppies for food, anesthesia, and ritual purposes dates back to at least the Neolithic Age. The Sumerian, Assyrian, Egyptian, Minoan, Greek, Roman, Persian and Arab Empires each made widespread use of opium, which was the most potent form of pain relief then available, allowing ancient surgeons to perform prolonged surgical procedures. Opium is mentioned in the most important medical texts of the ancient world, including the Ebers Papyrus and the writings of Dioscorides, Galen, and Avicenna. Widespread medical use of unprocessed opium continued through the American Civil War before giving way to morphine and its successors, which could be injected at a precisely controlled dosage. American morphine is still produced primarily from poppies grown and processed in India in the traditional manner, and remains the standard of pain relief for casualties of war.

Recreational use of the drug began in China in the fifteenth century, but was limited by its rarity and expense. Opium trade became more regular by the seventeenth century, when it was mixed with tobacco for smoking, and addiction was first recognized. Opium prohibition in China began in 1729, and was followed by nearly two centuries of exponentially increasing opium use. China had a positive balance sheet in trading with the British, which led to a decrease of the British silver stocks. Therefore, the British tried to encourage Chinese opium use to enhance their balance, and they delivered it from Indian provinces under British control. A massive confiscation of opium by the Chinese emperor, who tried to stop the opium deliveries, led to two Opium Wars in 1840 and 1858, in which consequence Britain suppressed China and traded opium all over the country. After 1860 opium use continued to increase with widespread domestic production in China, until more than a quarter of the male population was addicted by 1905. Recreational or addictive opium use in other nations remained rare into the late nineteenth century, recorded by an ambivalent literature that sometimes praised the drug.

Global regulation of opium began with the stigmatization of Chinese immigrants and opium dens, leading rapidly from town ordinances in the 1870s to the formation of the International Opium Commission in 1909. During this period the portrayal of opium in literature became squalid and violent, British opium trade was largely supplanted by domestic Chinese production, purified morphine and heroin became widely available for injection, and patent medicines containing opiates reached a peak of popularity. Opium was prohibited in many countries during the early twentieth century, leading to the modern pattern of opium production as a precursor for illegal recreational drugs or tightly regulated legal prescription drugs. Illicit opium production, now dominated by Afghanistan, has increased steadily in recent years to over 6600 tons yearly, nearly one-fifth the level of production in 1906. Opium for illegal use is often converted into heroin, which multiplies its potency to approximately twice that of morphine, and can be taken by intravenous injection, and is easier to smuggle.[citation needed]

Opium
Botanical Opium
Source plant(s) Papaver somniferum
Part(s) of plant sap
Geographic origin Middle East (?)
Active ingredients Morphine, Codeine
Main producers Afghanistan (primary), Thailand, Laos, Myanmar, Mexico, Colombia
Main consumers worldwide (#1: U.S.)
Legal status DEA schedule II or V
$300 per kilogram
Retail price $16,000 per kilogram
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Contents

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History

Ancient use (4200 BC - 800 BC)

Poppy crop from the Malwa region of India (probably Papaver somniferum var. album.)
Poppy crop from the Malwa region of India (probably Papaver somniferum var. album.[1])

The use of the opium poppy dates from time immemorial. At least seventeen finds of Papaver somniferum from Neolithic settlements have been reported throughout Switzerland, Germany, and Spain, including the placement of large numbers of poppy seed capsules at a burial site (the Cueva de los Murciélagos, or "Bat cave", in Spain), which have been carbon dated to 4200 B.C. Numerous finds of Papaver somniferum or Papaver setigerum from Bronze Age and Iron Age settlements have also been reported.[2] The first known cultivation of opium poppies was in Mesopotamia, approximately 3400 B.C., by Sumerians who called the plant Hul Gil, the "joy plant".[3][4] Tablets found at Nippur, a Sumerian spiritual center south of Baghdad, described the collection of poppy juice in the morning and its use in production of opium.[1] Cultivation continued in the Middle East by the Assyrians, who also collected poppy juice in the morning after scoring the pods with an iron scoop; they called the juice aratpa-pal, possibly the root of Papaver. Opium production continued under the Babylonians and Egyptians.

Opium was used with poison hemlock to put people quickly and painlessly to death, but it was also used in medicine. The Ebers Papyrus, ca. 1500 B.C., describes a way to "prevent the excessive crying of children" using grains of the poppy-plant strained to a pulp. Spongia somnifera, sponges soaked in opium, were used during surgery.[3] The Egyptians cultivated opium thebaicum in famous poppy fields around 1300 B.C. Opium was traded from Egypt by the Phoenicians and Minoans to destinations around the Mediterranean Sea, including Greece, Carthage, and Europe. By 1100 B.C. opium was cultivated on the Mediterranean island of Cyprus, where surgical quality knives were used to score the poppy pods, and opium was cultivated, traded, and smoked.[5] Opium was also mentioned after the Persian conquest of Assyria and Babylonia in the sixth century B.C.[1]

From the earliest finds opium has appeared to have ritual significance, and anthropologists have speculated that ancient priests may have used the drug as a proof of healing power.[3] In Egypt, the use of opium was generally restricted to priests, magicians, and warriors, its invention credited to Thoth, and it was said to have been given by Isis to Ra as treatment for a headache.[1] A figure of the Minoan "goddess of the narcotics", wearing a crown of three opium poppies, ca. 1300 B.C., was recovered from the Sanctuary of Gazi, Crete, together with a simple smoking apparatus.[5][6] The Greek gods Hypnos (Sleep), Nyx (Night), and Thanatos (Death) were depicted wreathed in poppies or holding poppies. Poppies also frequently adorned statues of Apollo, Asklepios, Pluto, Demeter, Aphrodite, Kybele and Isis, symbolizing nocturnal oblivion.[1]

Islamic Empire (600-1500 A.D.)

As the power of the Roman Empire declined, the lands to the south and east of the Mediterranean became incorporated into the Islamic Empire, which assembled the finest libraries and the most skilled physicians of the era. Many Muslims believe that the hadith of al-Bukhari prohibits every intoxicating substance as haraam, but the use of intoxicants in medicine has been widely permitted.[7] Dioscorides' five-volume De Materia Medica, the precursor of pharmacopoeias, remained in use (with some improvements in Arabic versions[8]) from the 1st to 16th centuries, and described opium, meconium and the wide range of uses prevalent in the ancient world.[9] Somewhere between 400 and 1200 AD, Arab traders introduced opium to China.[4][10][1] The Persian physician, Agha Bakr Muhammad ibn Zakariya al-Razi (845-930 A.D.), who was born near Tehran and maintained a laboratory and school in Baghdad, and was a student and critic of Galen, made use of opium in anesthesia and recommended its use for the treatment of melancholy in Man la Yahduruhu Al-Tabib, a home medical manual directed toward ordinary citizens for self-treatment if a doctor was not available.[11][12] The renowned opthalmologic surgeon Abu al-Qasim Ammar (936-1013 AD) relied on opium and mandrake as surgical anaesthetics, and wrote a treatise al-Tasrif that influenced medical thought well into the sixteenth century.[13][14] The Persian physician AbÅ« ‘AlÄ« al-Husayn ibn Sina (Avicenna) described opium as the most powerful of the stupefacients, by comparison with mandrake and other highly effective herbs, in The Canon of Medicine. This classic text was translated into Latin in 1175 and later into many other languages, and remained authoritative into the seventeenth century.[15] Åžerafeddin SabuncuoÄŸlu used opium in the fourteenth century Ottoman Empire to treat migraine headache, sciatica, and other painful ailments.[16]

Reintroduction to Western Medicine

Latin translation of Avicenna's Canon of Medicine, 1483
Latin translation of Avicenna's Canon of Medicine, 1483

Opium became stigmatized in Europe during the Inquisition as a Middle Eastern influence, and became a taboo subject in Europe from approximately 1300 to 1500 A.D. Manuscripts of Pseudo-Apuleius' fifth-century work from the tenth and eleventh centuries refer to the use of wild poppy Papaver agreste or Papaver rhoeas (identified as Papaver silvaticum) instead of Papaver somniferum for inducing sleep and relieving pain.[17]

The use of Paracelsus' laudanum was introduced to Western medicine in 1527, when Philip Aureolus Theophrastus Bombast von Hohenheim returned from his wanderings in Arabia with a famous sword, within the pommel of which he kept "Stones of Immortality" compounded from opium thebaicum, citrus juice, and "quintessence of gold".[4][18][19] The name "Paracelsus" was a pseudonym signifying him the equal or better of Aulus Cornelius Celsus, whose text, which described the use of opium or a similar preparation, had recently been translated and reintroduced to medieval Europe.[20] The Canon of Medicine, the standard medical textbook that Paracelsus burned in a public bonfire three weeks after being appointed professor at the University of Basel, also described the use of opium, though many Latin translations were of poor quality.[21] "Laudanum" was originally the sixteenth-century term for a medicine associated with a particular physician that was widely well-regarded, but became standardized as "tincture of opium", a solution of opium in ethyl alcohol, which Paracelsus has been credited with developing. During his lifetime, Paracelsus was viewed as an adventurer who challenged the theories and mercenary motives of contemporary medicine with dangerous chemical therapies, but his therapies marked a turning point in Western medicine. In the seventeenth century laudanum was recommended for pain, sleeplessness, and diarrhea by Thomas Sydenham,[22] the renowned "father of English medicine" or "English Hippocrates", to whom is attributed the quote, "Among the remedies which it has pleased Almighty God to give to man to relieve his sufferings, none is so universal and so efficacious as opium."[23] Use of opium as a cure-all was reflected in the formulation of mithridatium described in the 1728 Chambers Cyclopedia, which included true opium in the mixture. Subsequently laudanum became the basis of many popular patent medicines of the nineteenth century.

The standard medical use of opium persisted well into the nineteenth century. U.S president William Henry Harrison was treated with opium in 1841, and in the American Civil War, the Union Army used 2.8 million ounces of opium tincture and powder and about 500,000 opium pills.[1] During this time of popularity, users called opium "God's Own Medicine".[24]

Recreational use

An opium den in 18-century China through the eyes of a Western artist.
An opium den in 18-century China through the eyes of a Western artist.
A typical depiction of an opium smoking scene in London's Limehouse district based on fictional accounts of the day.
A typical depiction of an opium smoking scene in London's Limehouse district based on fictional accounts of the day.
Main article: Opium den

The earliest clear description of the use of opium as a recreational drug came from Xu Boling, who wrote in 1483 that opium was "mainly used to aid masculinity, strengthen sperm and regain vigor", and that it "enhances the art of alchemists, sex and court ladies." He described an expedition sent by the Chenghua Emperor in 1483 to procure opium for a price "equal to that of gold" in Hainan, Fujian, Zhejiang, Sichuan and Shaanxi where it is close to Xiyu. A century later Li Shizhen listed standard medical uses of opium in his renowned Compendium of Materia Medica (1578), but also wrote that "lay people use it for the art of sex", in particular the ability to "arrest seminal emission". This association of opium with sex continued in China until the twentieth century. Opium smoking began as a privilege of the elite, and remained a great luxury into the early nineteenth century, but by 1861, Wang Tao wrote that opium was used even by rich peasants, and even a small village without a rice store would have a shop where opium was sold.[25]

Smoking of opium came on the heels of tobacco smoking, and may have been encouraged by a brief ban on the smoking of tobacco by the Ming emperor, ending in 1644 with the Qing dynasty, which had encouraged smokers to mix in increasing amounts of opium.[1] In 1705, Wang Shizhen wrote that "nowadays, from nobility and gentlemen down to slaves and women, all are addicted to tobacco". Tobacco in that time was frequently mixed with other herbs (this continues with clove cigarettes to the modern day), and opium was one component in the mixture. Tobacco mixed with opium was called madak (or madat), and became popular throughout China and its seafaring trade partners (such as Taiwan, Java and the Philippines) in the seventeenth century.[25] In 1712, Engelbert Kaempfer described addiction to madak: "No commodity throughout the Indies is retailed with greater profit by the Batavians than opium, which [its] users cannot do without, nor can they come by it except it be brought by the ships of the Batavians from Bengal and Coromandel."[10]

Fueled in part by the 1729 ban on madak, which at first effectively exempted pure opium as a potentially medicinal product, the smoking of pure opium became more popular in the eighteenth century. In 1736, the smoking of pure opium was described by Huang Shujing, involving a pipe made from bamboo rimmed with silver, stuffed with palm slices and hair, fed by a clay bowl in which a globule of molten opium was held over the flame of an oil lamp. This elaborate procedure, requiring the maintenance of pots of opium at just the right temperature for a globule to be scooped up with a needle-like skewer for smoking, formed the basis of a craft of 'paste-scooping' by which servant girls could become prostitutes as the opportunity arose.[25]

Beginning in eighteenth century China, famine and political upheaval, as well as rumors of wealth to be had in nearby Southeast Asia, led to the Chinese Diaspora. Chinese emigrants to cities such as San Francisco, London, and New York brought with them the Chinese manner of opium smoking and the social traditions of the opium den.[26][27] The Indian Diaspora distributed opium-eaters in the same way, and both social groups survived as "lascars" (seamen) and "coolies" (manual laborers). French sailors provided another major group of opium smokers, having contracted the habit in French Indochina, where the drug was promoted by the colonial government as a monopoly and source of revenue.[28][29] Among white Europeans opium was more frequently consumed as laudanum or in patent medicines. Britain's All-India Opium Act of 1878 formalized social distinctions, limiting recreational opium sales to registered Indian opium-eaters and Chinese opium-smokers, and prohibiting its sale to workers from Burma.[30] Likewise American law sought to contain addiction to immigrants by prohibiting Chinese from smoking opium in the presence of a white man.[31]

Because of the low social status of immigrant workers, contemporary writers and media had little trouble portraying opium dens as seats of vice, white slavery, gambling, knife and revolver fights, a source for drugs causing deadly overdoses, with the potential to addict and corrupt the white population. By 1919, anti-Chinese riots attacked Limehouse, the Chinatown of London. Chinese men were deported for playing puck-apu, a popular gambling game, and sentenced to hard labor for opium possession. Both the immigrant population and the social use of opium fell into decline.[32][33] Yet despite lurid literary accounts to the contrary, nineteenth century London was not a hotbed of opium smoking. The total lack of photographic evidence of opium smoking in Britain, as opposed to the relative abundance of historical photos depicting opium smoking in North America and France, indicates that the infamous Limehouse opium smoking scene was little more than fantasy on the part of British writers of the day who were intent on scandalizing their readers while drumming up the threat of the "yellow peril".[34][35]

Prohibition and conflict in China

Destruction of opium in China
Destruction of opium in China
Main articles: Prohibition (drugs) and Opium Wars

Opium prohibition began in 1729, when Emperor Yongzheng of the Qing Dynasty, disturbed by madak smoking at court and carrying out the government's role of upholding Confucian virtue, officially prohibited the import of opium, except for a small amount for medicinal purposes. The ban punished sellers and opium den keepers, but not users of the drug.[10] Opium prohibition in China continued until 1860, and was later resumed.

English opium ships
English opium ships

Under the Qing Dynasty, China opened itself to foreign trade under the Canton System through the port of Guangzhou (Canton), and traders from the British East India Company began visiting the port by the 1690s. Due to the growing British demand for Chinese tea, and the Chinese disinterest in British commodities other than silver, the British became interested in opium as a high-value commodity for which China was not self sufficient. The British traders had been purchasing small amounts of opium from India for trade since Ralph Fitch first visited in the mid-sixteenth century.[10] Trade in opium was standardized, with production of balls of raw opium, 1.1 to 1.6 kilograms, 30% water content, wrapped in poppy leaves and petals, shipped in chests of 60-65 kilograms (one picul).[10] Chests of opium were sold in auctions in Calcutta with the understanding that the independent purchasers would then smuggle it into China (see Opium Wars).

After the 1757 Battle of Plassey and 1764 Battle of Buxar, the British East India Company gained the power to act as diwan of Bengal, Bihar, and Orissa (See company rule in India). This allowed the company to pursue a monopoly on opium production and export in India, to encourage ryots to cultivate the cash crops of indigo and opium with cash advances, and to prohibit the "hoarding" of rice. This strategy led to the increase of the land tax to 50% of the value of crops, the starvation of ten million people in the Bengal famine of 1770, and the doubling of East India Company profits by 1777. Beginning in 1773 the British government began enacting oversight of the company's operations, culminating in the establishment of British India in response to the Indian Rebellion of 1857. Bengal opium was highly prized, commanding twice the price of the domestic Chinese product, which was regarded as inferior in quality.[36]

Some competition came from the newly independent United States, which began to compete in Guangzhou (Canton) selling Turkish opium in the 1820s. Portuguese traders also brought opium from the independent Malwa states of western India, although by 1820 the British were able to restrict this trade by charging "pass duty" on the opium when it was forced to pass through Bombay to reach an entrepot.[10] Despite drastic penalties and continued prohibition of opium until 1860, opium importation rose steadily from 200 chests per year under Yongzheng to 1,000 under Qianlong, 4,000 under Jiaqing, and 30,000 under Daoguang.[37] The illegal sale of opium became one of the world's most valuable single commodity trades, and has been called "the most long continued and systematic international crime of modern times".[38]

In response to the ever-growing number of Chinese people becoming addicted to opium, Daoguang of the Qing Dynasty took strong action to halt the import of opium, including the seizure of cargo. In 1838 the Chinese Commissioner Lin Zexu destroyed 20,000 chests of opium in Guangzhou (Canton).[10] Given that a chest of opium was worth nearly $1,000 in 1800, this was a substantial economic loss. The British, not willing to replace the cheap opium with costly silver, began the First Opium War in 1840, winning Hong Kong and trade concessions in the first of a series of Unequal Treaties.

Map showing the amount of Opium produced in China in 1908
Map showing the amount of Opium produced in China in 1908

Following China's defeat in the Second Opium War in 1858, China was forced to legalize opium and began massive domestic production. Importation of opium peaked in 1879 at 6,700 tons, and by 1906 China was producing 85% of the world's opium, some 35,000 tons, and 27% of its adult male population was addicted - 13.5 million addicts consuming 39,000 tons of opium yearly.[39] From 1880 to the beginning of the Communist era the British attempted to discourage the use of opium in China, but this effectively promoted the use of morphine, heroin, and cocaine, further exacerbating the problem of addiction.[40]

Scientific evidence of the pernicious nature of opium use was largely undocumented in the 1890s when Protestant missionaries in China decided to strengthen their opposition to the trade by compiling data which would demonstrate the harm the drug did. Faced with the problem that many Chinese associated Christianity with opium, partly due to the arrival of early Protestant missionaries on opium clippers, at the 1890 Shanghai Missionary Conference they agreed to establish the Permanent Committee for the Promotion of Anti-Opium Societies in an attempt to overcome this problem and to arouse public opinion against the opium trade. The members of the committee were John G Kerr, MD, American Presbyterian Mission in Canton; BC Atterbury MD, American Presbyterian Mission in Peking, Archdeacon Arthur E Moule, Church Missionary Society in Shanghai, Henry Whitney MD, American Board of Commissioners for foreign Missions in Foochow, the Rev Samuel Clarke, China Inland Mission in Kweiyang; the Rev Arthur Shorrock, English Baptist Mission in Taiyuan and the Rev Griffith John, London Mission Society in Hankow. [41] These missionaries were generally outraged over the British government’s Royal Commission on Opium visiting India but not China. Accordingly, the missionaries first organized the Anti-Opium League in China among their colleagues in every mission station in China. American missionary Hampden Coit DuBose acted as first president. This organization which had elected national officers and held an annual national meeting, was instrumental in gathering data from every Western-trained medical doctor in China which was then published as William Hector Park, compiled Opinions of Over 100 Physicians on the Use of Opium in China (Shanghai: American Presbyterian Mission Press, 1899). The vast majority of these medical doctors were missionaries, the survey also included doctors who were in private practices, particularly in Shanghai and Hong Kong, as well as Chinese who had been trained in medical schools in Western countries. In England, the home director of the China Inland Mission, Benjamin Broomhall was an active opponent of the Opium trade, writing two books to promote the banning of opium smoking: The Truth about Opium Smoking and The Chinese Opium Smoker. In 1888 Broomhall formed and became secretary of the Christian Union for the Severance of the British Empire with the Opium Traffic and editor of its periodical, "National Righteousness". He lobbied the British Parliament to stop the opium trade. He and James Laidlaw Maxwell appealed to the London Missionary Conference of 1888 and the Edinburgh Missionary Conference of 1910 to condemn the continuation of the trade. When Broomhall was dying, his son Marshall read to him from The Times the welcome news that an agreement had been signed ensuring the end of the opium trade within two years.

Official Chinese resistance to opium was renewed on September 20, 1906 with an anti-opium initiative intended to eliminate the drug problem within ten years. The program relied on the turning of public sentiment against opium, with mass meetings at which opium paraphernalia was publicly burned, as well as coercive legal action and the granting of police powers to organizations such as the Fujian Anti-Opium Society. Smokers were required to register for licenses for gradually reducing rations of the drug. Addicts sometimes turned to missionaries for treatment for their addiction, though many associated these foreigners with the drug trade. The program was counted as a substantial success, with a cessation of direct British opium exports to China (but not Hong Kong[42]) and most provinces declared free of opium production. Nonetheless, the success of the program was only temporary, with opium use rapidly increasing during the disorder following the death of Yuan Shikai in 1916.[43]

Beginning in 1915, Chinese nationalist groups came to describe the period of military losses and Unequal Treaties as the "Century of National Humiliation", later defined to end with the conclusion of the Chinese Civil War in 1949.[44] The Mao Zedong government is generally credited with eradicating both consumption and production of opium during the 1950s using unrestrained repression and social reform. Ten million addicts were forced into compulsory treatment, dealers were executed, and opium-producing regions were planted with new crops. Remaining opium production shifted south of the Chinese border into the Golden Triangle region, at times with the involvement of Western intelligence agencies.[36] The remnant opium trade primarily served Southeast Asia, but spread to American soldiers during the Vietnam War, with 20% of soldiers regarding themselves as addicted during the peak of the epidemic in 1971. In 2003, China was estimated to have four million regular drug users and one million registered drug addicts.[45]

See also: Japanese opium policy in Taiwan (1895-1945)

Prohibition outside China

There were no legal restrictions on the importation or use of opium in the United States until the San Francisco, California Opium Den Ordinance which banned dens for public smoking of opium in 1875, a measure fueled by anti-Chinese sentiment and the perception that whites were starting to frequent the dens. This was followed by an 1891 California law requiring that narcotics carry warning labels and that their sales be recorded in a registry, amendments to the California Pharmacy and Poison Act in 1907 making it a crime to sell opiates without a prescription, and bans on possession of opium or opium pipes in 1909.[46]

At the U.S. federal level, the legal actions taken reflected constitutional restrictions under the Enumerated powers doctrine prior to reinterpretation of the Commerce clause, which did not allow the federal government to enact arbitrary prohibitions but did permit arbitrary taxation.[47] Beginning in 1883 opium importation was taxed at $6 to $300 per pound, until the Opium Exclusion Act of 1909 prohibited the importation of opium altogether. In a similar manner the Harrison Narcotics Tax Act of 1914, passed in fulfillment of the International Opium Convention of 1912, nominally placed a tax on the distribution of opiates, but served as a de facto prohibition of the drugs. Today opium is regulated by the Drug Enforcement Administration under the Controlled Substances Act.

Following passage of a regional law in 1895, Australia's Aboriginal Protection and restriction of the sale of opium act 1897, addressed opium addiction among Aborigines, though it soon became a general vehicle for depriving them of basic rights by administrative regulation. Opium sale was prohibited to the general population in 1905, and smoking and possession was prohibited in 1908.[48]

Hardening of Canadian attitudes toward Chinese opium users and fear of a spread of the drug into the white population led to the effective criminalization of opium for non-medical use in Canada between 1908 and the mid-1920s.[49]

In 1909 the International Opium Commission was founded, and by 1914 thirty-four nations had agreed that the production and importation of opium should be diminished. In 1924, sixty-two nations participated in a meeting of the Commission. Subsequently this role passed to the League of Nations, and all signatory nations agreed to prohibit the import, sale, distribution, export, and use of all narcotic drugs, except for medical and scientific purposes. This role was later taken up by the International Narcotics Control Board of the United Nations under Article 23 of the Single Convention on Narcotic Drugs, and subsequently under the Convention on Psychotropic Substances. Opium-producing nations are required to designate a government agency to take physical possession of licit opium crops as soon as possible after harvest and conduct all wholesaling and exporting through that agency.[1]

Obsolescence

Bayer heroin bottle
Bayer heroin bottle

Opium has gradually been superseded by a variety of purified, semi-synthetic, and synthetic opioids with progressively stronger effect, and by other general anesthesia. This process began in 1817, when Friedrich Wilhelm Adam Sertürner reported the isolation of pure morphine from opium after at least thirteen years of research and a nearly disastrous trial on himself and three boys.[50] The great advantage of purified morphine was that a patient could be treated with a known dose - whereas with raw plant material, as Gabriel Fallopius once lamented, "if soporifics are weak they do not help; if they are strong they are exceedingly dangerous." Morphine was the first pharmaceutical isolated from a natural product, and this success encouraged the isolation of other alkaloids: by 1820, isolations of narcotine, strychnine, veratrine, colchicine, caffeine, and quinine were reported. Morphine sales began in 1827, by Heinrich Emanuel Merck of Darmstadt, and helped him expand his family pharmacy into the massive Merck KGaA pharmaceutical company.

Codeine was isolated in 1832 by Robiquet.

The use of diethyl ether and chloroform for general anesthesia began in 1846-1847, and rapidly displaced the use of opiates and tropane alkaloids from Solanaceae due to their relative safety.[51]

Heroin, the first semi-synthetic opiate, was first synthesized in 1874, but was not pursued until its rediscovery in 1897 by Felix Hoffmann at the Bayer pharmaceutical company in Elberfeld, Germany. From 1898 through to 1910 heroin was marketed as a non-addictive morphine substitute and cough medicine for children. By 1902, sales made up 5% of the company's profits, and "heroinism" had attracted media attention.[52] Oxycodone, a thebaine derivative similar to codeine, was introduced by Bayer in 1916 and promoted as a less-addictive analgesic. Preparations of the drug such as Percocet and Oxycontin remain popular to this day.

A range of synthetic opioids such as methadone (1937), pethidine (1939), fentanyl (late 1950s), and derivatives thereof have been introduced, and each is preferred for certain specialized applications. Nonetheless, morphine remains the drug of choice for American combat medics, who carry packs of syrettes containing 16 milligrams each for use on severely wounded soldiers.[53] No drug has yet been found that can match the painkilling effect of opium without also duplicating much of its addictive potential.

Modern production and usage

Papaver somniferum

Scoring the poppy pod.
Scoring the poppy pod.
Raw opium
Raw opium
Main article: Opium poppy

In South American countries, opium poppies (Papaver somniferum) are technically illegal, but nonetheless appear in some nurseries as ornamentals. They are popular and attractive garden plants, whose flowers vary greatly in color, size and form. A modest amount of domestic cultivation in private gardens is not usually subject to legal controls. In part this tolerance reflects variation in addictive potency: a cultivar for opium production, Papaver somniferum L. elite, contains 92% morphine, codeine, and thebaine in its latex alkaloids, whereas the condiment cultivar "Marianne" has only one-fifth this total, with the remaining alkaloids made up mostly of narcotoline and noscapine.[54]

Seed capsules can be dried and used for decorations, but they also contain morphine, codeine, and other alkaloids. These pods can be boiled in water to produce a bitter tea that induces a long-lasting intoxication (See Poppy tea). If allowed to mature, poppy pods can be crushed into "poppy straw" and used to produce lower quantities of morphinans. In poppies subjected to mutagenesis and selection on a mass scale, researchers have been able to use poppy straw to obtain large quantities of oripavine, a precursor to opioids and antagonists such as naltrexone.[55]

Poppyseeds are a common and flavorsome topping for breads and cakes. One gram of poppy seeds contains up to 33 micrograms of morphine and 14 micrograms of codeine, and the Substance Abuse and Mental Health Services Administration formerly mandated that all drug screening laboratories use a standard cutoff of 300 nanograms per milliliter in urine samples. A single poppy seed roll (0.76 grams of seeds) usually did not produce a positive drug test, but a positive result was observed from eating two rolls. A slice of poppy seed cake containing nearly five grams of seeds per slice produced positive results for 24 hours. Such results are viewed as false positive indications of drug abuse, and were the basis of a legal defense.[56][57] On November 30, 1998, the standard cutoff was increased to 2000 nanograms (two micrograms) per milliliter.[58] During the Communist era in Eastern Europe, poppy stalks sold in bundles by farmers were processed by users with household chemicals to make kompot ("Polish heroin"), and poppy seeds were used to produce koknar, an opiate.[59]

Harvesting and processing

When grown for opium production, the skin of the ripening pods of these poppies is scored by a sharp blade at a time carefully chosen so that neither rain, wind, nor dew can spoil the exudation of white, milky latex, usually in the afternoon. Incisions are made while the pods are still raw, with no more than a slight yellow tint, and must be shallow to avoid penetrating hollow inner chambers or loculi while cutting into the lactiferous vessels. In India, the special tool used to make the incisions is called a nushtar, and carries three or four blades three millimeters apart, which are scored upward along the pod. Incisions are made three or four times at intervals of two to three days, and each time the "poppy tears", which dry to a sticky brown resin, are collected the following morning. One acre harvested in this way can produce three to five kilograms of raw opium.[60] In the Soviet Union pods were typically scored horizontally, and opium was collected three times, or else one or two collections were followed by isolation of opiates from the ripe capsules. Oil poppies, an alternative strain of P. somniferum, were also used for production of opiates from their capsules and stems.[61]

Black tar opium seized in Afghanistan, spring 2005
Black tar opium seized in Afghanistan, spring 2005

Raw opium may be sold to a merchant or broker on the black market, but it usually does not travel far from the field before it is refined into morphine base, because pungent, jelly-like raw opium is bulkier and harder to smuggle. Crude laboratories in the field are capable of refining opium into morphine base by a simple acid-base extraction. A sticky, brown paste, morphine base is pressed into bricks and sun-dried, and can either be smoked or processed into heroin.[4]

Heroin is widely preferred because of increased potency. One study in postaddicts found heroin to be approximately 2.2 times more potent than morphine by weight with a similar duration; at these relative quantities they could distinguish the drugs subjectively but had no preference.[62] Heroin was also found to be twice as potent as morphine in surgical anesthesia.[63] Morphine is converted into heroin by a simple chemical reaction with acetic anhydride, followed by a varying degree of purification.[64][65] Especially in Mexican production, opium may be converted directly to "black tar heroin" in a simplified procedure. This form predominates in the U.S. west of the Mississippi. Relative to other preparations of heroin, it has been associated with a dramatically increased rate of HIV transmission among intravenous drug users (4% in Los Angeles vs. 40% in New York) due to technical requirements of injection, although it is also associated with greater risk of venous sclerosis and necrotizing fasciitis.[66]

Illegal production

Main producers of opium for the heroin trade
Main producers of opium for the heroin trade
Approximate global opium production for recreational purposes
Approximate global opium production for recreational purposes
See also: Opium production in Afghanistan and Illegal drug trade

Opium production has fallen greatly since 1906, when 41,000 tons were produced, but because 39,000 tons of that year's opium were consumed in China, overall usage in the rest of the world was much lower.[67] In 1980, 2,000 tons of opium supplied all legal and illegal uses.[10] Recently, opium production has increased considerably, surpassing 5,000 tons in 2002. In 2002 the price for one kilogram of opium was $300 for the farmer, $800 for purchasers in Afghanistan, and $16,000 on the streets of Europe before conversion into heroin.[68]

Following documented trends of increasing availability mirroring increased American military and geo-political regional involvement, see the Golden Triangle region of Southeast Asia (particularly Myanmar), Colombia and Mexico, Afghanistan is currently the primary producer of the drug. After regularly producing 70% of the world's opium, Afghanistan decreased production to 74 tons per year under a ban by the Taliban in 2000, although the ban may have been intended primarily to boost prices after the country accumulated a stockpile with over two years' supply.[69] After the 2001 war in Afghanistan, production increased again. According to DEA statistics, Afghanistan's production of oven-dried opium increased to 1,278 tons in 2002, more than doubled by 2003, and nearly doubled again during 2004. In late 2004, the U.S. government estimated that 206,000 hectares were under poppy cultivation, 4.5% of the country's total cropland, and produced 4,200 metric tons of opium, 87% of the world's supply, yielding 60% of Afghanistan's gross domestic product.[70] In 2006, the UN Office on Drugs and Crime estimated production to have risen 59% to 407,000 acres (1,650 km²) in cultivation, yielding 6,100 tons of opium, 92% of the world's supply.[71] The value of the resulting heroin was estimated at $3.5 billion, of which Afghan farmers were estimated to have received $700 million in revenue (of which the Taliban have been estimated to have collected anywhere from tens of millions to $140 million in taxes).[72] For farmers, the crop can be up to ten times more profitable than wheat.

An increasingly large fraction of opium is processed into morphine base and heroin in drug labs in Afghanistan. Despite an international set of chemical controls designed to restrict availability of acetic anhydride, it enters the country, perhaps through its Central Asian neighbors which do not participate. A counternarcotics law passed in December 2005 requires Afghanistan to develop registries or regulations for tracking, storing, and owning acetic anhydride.[73]

Besides Afghanistan, smaller quantities of opium are produced in Pakistan, the Golden Triangle region of Southeast Asia (particularly Myanmar), Colombia and Mexico.

Legal production

Main article: Opium licensing

Legal opium production is allowed under the United Nations Single Convention on Narcotic Drugs and other international drug treaties, subject to strict supervision by the law enforcement agencies of individual countries. The leading legal production method is the Gregory process, whereby the entire poppy, excluding roots and leaves, is mashed and stewed in dilute acid solutions. The alkaloids are then recovered via acid-base extraction and purified. This process was developed in the UK during World War II, when wartime shortages of many essential drugs encouraged innovation in pharmaceutical processing.

Legal production in India is much more traditional. As of 1996, opium was collected by farmers who licensed to grow 0.1 hectare of opium poppies (0.24 acres), who to maintain their licenses needed to sell 4.5 kilograms of unadulterated raw opium paste at a fixed government price of 32 rupees ($8 US) per kilogram. One kilogram represents two days' work for a family. Some additional money is made by drying the poppy heads and collecting poppy seeds, and a small fraction of opium beyond the quota may be consumed locally or diverted to the black market. The opium paste is sun-dried and stirred in large pans before it is packed into cases of 60 kilograms for export. Purification of chemical constituents is done in India for domestic production, but typically done abroad by foreign importers.[74]

Legal opium importation from India and Turkey is conducted by Mallinckrodt, Noramco, Abbott Laboratories, and Purdue Pharma in the United States, and legal opium production is conducted by GlaxoSmithKline, Johnson and Johnson, Johnson Matthey, and Mayne in Tasmania, Australia; Sanofi Aventis in France; Shionogi Pharmaceutical in Japan; and MacFarlan Smith in the United Kingdom.[75] The UN treaty requires that every country submit annual reports to the International Narcotics Control Board, stating that year's actual consumption of many classes of controlled drugs as well as opioids, and projecting required quantities for the next year. This is to allow trends in consumption to be monitored, and production quotas allotted.

A recent proposal from the European Senlis Council hopes to solve the problems caused by the massive quantity of opium produced illegally in Afghanistan, most of which is converted to heroin, and smuggled for sale in Europe and the USA. This proposal is to license Afghan farmers to produce opium for the world pharmaceutical market, and thereby solve another problem, that of chronic underuse of potent analgesics where required within developing nations. Part of the proposal is to overcome the "80-20 rule" that requires the U.S. to purchase 80% of its legal opium from India and Turkey to include Afghanistan, by establishing a second-tier system of supply control that complements the current INCB regulated supply and demand system by providing poppy-based medicines to countries who cannot meet their demand under the current regulations. Senlis arranged a conference in Kabul that brought drug policy experts from around the world to meet with Afghan government officials to discuss internal security, corruption issues, and legal issues within Afghanistan.[76] In June 2007, the Council launched a "Poppy for Medicines" project that provides a technical blueprint for the implementation of an integrated control system within Afghan village-based poppy for medicine projects: the idea promotes the economic diversification by redirecting proceeds from the legal cultivation of poppy and production of poppy-based medicines (See Senlis Council).[77]

Cultivation in the UK

In late 2006, the British government permitted the pharmaceutical company Macfarlan Smith (a Johnson Matthey company) to cultivate opium poppies in England for medicinal reasons, after Macfarlan Smith's primary source, India, decided to increase the price of export opium latex. This move is well received by British farmers, with a major opium poppy field based in Didcot, England. The British government has contradicted the Home Office's suggestion that opium cultivation can be legalized in Afghanistan for exports to the United Kingdom, helping lower poverty and internal fighting whilst helping NHS to meet the high demand for morphine and diamorphine. Opium poppy cultivation in the United Kingdom does not need a licence, however, a licence is required for those wishing to extract opium for medicinal products.[78]

Consumption

In the industrialized world, the USA is the world's biggest consumer of prescription opioids, with Italy one of the lowest.[79] Most opium imported into the United States is broken down into its alkaloid constituents, and whether legal or illegal, most current drug use occurs with processed derivatives such as heroin rather than with pure and untouched opium.

Intravenous injection of opiates is most used: by comparison with injection, "dragon chasing" (heating of heroin with barbital on a piece of foil) and "ack ack" (smoking of cigarettes containing heroin powder) are only 40% and 20% efficient, respectively.[80] One study of British heroin addicts found a 12-fold excess mortality ratio (1.8% of the group dying per year).[81] Most heroin deaths result not from overdose per se, but combination with other depressant drugs such as alcohol or benzodiazepines.[82]

An Akha man smokes a pipe. Although this pipe was described as an opium pipe by the photographer, a true opium pipe requires an external heat source.  Still, opium can be smoked by mixing it with tobacco, as in madak and ack ack.
An Akha man smokes a pipe. Although this pipe was described as an opium pipe by the photographer, a true opium pipe requires an external heat source. Still, opium can be smoked by mixing it with tobacco, as in madak and ack ack.

The smoking of opium does not involve the pyrolysis of the material as might be imagined. Rather the prepared opium is indirectly heated to temperatures at which the active alkaloids, chiefly morphine, are vaporized. In the past, smokers would utilize a specially designed opium pipe which had a removable knob-like pipe-bowl of fired earthenware attached by a metal fitting to a long, cylindrical stem.[83] A small "pill" of opium about the size of a pea would be placed on the pipe-bowl, which was then heated by holding it over an opium lamp, a special oil lamp with a distinct funnel-like chimney to channel heat into a small area. The smoker would lie on his or her side in order to guide the pipe-bowl and the tiny pill of opium over the stream of heat rising from the chimney of the oil lamp and inhale the vaporized opium fumes as needed. Several pills of opium were smoked at a single session depending on the smoker's tolerance to the drug. The effects could last up to twelve hours.

In Eastern culture, opium is more commonly used in the form of paregoric to treat diarrhea. This is a weaker solution than laudanum, an alcoholic tincture which was prevalently used as a pain medication and sleeping aid. Tincture of opium has been prescribed for, among other things, severe diarrhea.[84] Taken 30 minutes prior to meals it will significantly slow intestinal motility, giving the intestines greater time to absorb fluid in the stool.

Chemical and physiological properties

Morphine is the primary biologically-active chemical constituent of opium.
Morphine is the primary biologically-active chemical constituent of opium.
See also: Opioid, Opiate, and Morphinan

Opium contains two main groups of alkaloids. Those that use opium are commonly referred to as "opiats" (Coined by James St. Louis). Phenanthrenes include morphine, codeine, and thebaine, and are the main narcotic constituents. Isoquinolines such as papaverine have no significant central nervous system effects and are not regulated under the Controlled Substances Act. Morphine is by far the most prevalent and important alkaloid in opium, consisting of 10%-16% of the total, and is responsible for most of its harmful effects such as lung edema, respiratory difficulties, coma, or cardiac or respiratory collapse, with a normal lethal dose of 120 to 250 milligrams[85]—the amount found in approximately two grams of opium.[86] Morphine binds to and activates μ-opioid receptors in the brain, spinal cord, stomach and intestine. Regular use leads to physical tolerance and dependence. Chronic opium addicts in 1906 China[87] or modern-day Iran[88] consume an average of eight grams daily.

Both analgesia and drug addiction are functions of the mu opioid receptor, the class of opioid receptor first identified as responsive to morphine. Tolerance is associated with the superactivation of the receptor, which may be affected by the degree of endocytosis caused by the opioid administered, and leads to a superactivation of cyclic AMP signalling.[89] Long-term use of morphine in palliative care and management of chronic pain can be managed without the development of drug tolerance or (physical dependence). Many techniques of drug treatment exist, including pharmacologically based treatments with naltrexone, methadone, or ibogaine [90].

Cultural references

There is a rich and longstanding literature by and about opium users. Thomas De Quincey's 1822 Confessions of an English Opium-Eater is one of the first and most famous literary accounts of opium addiction written from the point of view of an addict, and details both the pleasures and the dangers of the drug. De Quincey writes about the great English Romantic poet Samuel Taylor Coleridge (1772-1834), whose poem "Kubla Khan" is also widely considered to be a poem of the opium experience. Coleridge began using opium in 1791 after developing jaundice and rheumatic fever, and became a full addict after a severe attack of the disease in 1801, requiring 80-100 drops of laudanum daily.[91] "The Lotos-Eaters", an 1832 poem by Alfred Lord Tennyson, reflects the generally favorable British attitude toward the drug. In The Count of Monte Cristo (1844), by Alexandre Dumas, père, the Count is assuaged by an edible form of opium, and his experience with it is depicted vividly.

Edgar Allan Poe presents opium in a more disturbing context in his 1838 short story "Ligeia", in which the narrator, deeply distraught for the loss of his beloved, takes solace in opium until he "had become a bounden slave in the trammels of opium", unable to distinguish fantasy from reality after taking immoderate doses of opium. In music, Hector Berlioz' 1830 Symphony Fantastique tells the tale of an artist who has poisoned himself with opium while in the depths of despair for a hopeless love. Each of the symphony's five movements takes place at a different setting and with increasingly audible effects from the drug. For example, in the fourth movement, "Marche au Supplice", the artist dreams that he is walking to his own execution. In the fifth movement, "Songe d’une Nuit du Sabbat", he dreams that he is at a witch's orgy, where he witnesses his beloved dancing wildly along to the demented Dies Irae.

Towards the end of the nineteenth century, references to opium and opium addiction in the context of crime and the foreign underclass abound in English literature, such as in the opening paragraphs of Charles Dickens's 1870 serial The Mystery of Edwin Drood and in Arthur Conan Doyle's 1891 Sherlock Holmes short story The Man with the Twisted Lip. In Oscar Wilde's 1890 The Picture of Dorian Gray, the protagonist visits an opium den 'for forgetfulness', unable to bear the guilt and shame of commiting murder. Opium likewise underwent a transformation in Chinese literature, becoming associated with indolence and vice by the early twentieth century.[43] Perhaps the best-known literary reference to opium is Karl Marx's metaphor in his "Contribution to the Critique of Hegel's 'Philosophy of Right'", where he refers to religion as "the opium of the people." (This phrase is more commonly quoted as "the opiate of the masses.")

In the twentieth century, as the use of opium was eclipsed by morphine and heroin, its role in literature became more limited, and often focused on issues related to its prohibition. In The Good Earth by Pearl S. Buck, Wang Lung, the protagonist, gets his troublesome uncle and aunt addicted to opium in order to keep them out of his hair. William S. Burroughs autobiographically describes the use of opium beside that of its derivatives. His associate Jack Black's memoir You Can't Win chronicles one man's experience both as an onlooker in the opium dens of San Francisco, and later as a "hop fiend" himself. The book and subsequent movie, The Wonderful Wizard of Oz, may allude to opium at one point in the story, when Dorothy and her friends are drawn into a field of poppies, in which they fall asleep.

See also

References

  1. ^ a b c d e f g h i Paul L. Schiff, Jr. (2002). Opium and its alkaloids. Retrieved on 2007-05-08.
  2. ^ Suzanne Carr (1995). MS thesis. Retrieved on 2007-05-16. (citing Andrew Sherratt)
  3. ^ a b c M J Brownstein (1993-06-15). "A brief history of opiates, opioid peptides, and opioid receptors". Proc Natl Acad Sci U S A 90 (12): 5391–5393. Retrieved on 2007-05-10.
  4. ^ a b c d PBS Frontline (1997). The Opium Kings. Retrieved on 2007-05-16.
  5. ^ a b P. G. Kritikos and S. P. Papadaki (1967-01-01). "The early history of the poppy and opium". Journal of the Archaeological Society of Athens. Retrieved on 2007-05-26.
  6. ^ E. Guerra Doce (2006-01-01). "Evidencias del consumo de drogas en Europa durante la Prehistoria" (in Spanish). Trastornos Adictivos 8 (1): 53-61. Retrieved on 2007-05-10. (includes image)
  7. ^ Ibraham B. Syed. Alcohol and Islam.
  8. ^ Islamic Medical Manuscripts at the National Library of Medicine: a note on pharmaceutics. Retrieved on 2007-06-06.
  9. ^ Julius Berendes (1902). De Materia Medica (German). Retrieved on 2007-05-10.
  10. ^ a b c d e f g h Carl A. Trocki (2002). Opium as a commodity and the Chinese drug plague. Retrieved on 2005-06-07.
  11. ^ Answers.com: al-Razi.
  12. ^ (2002-01) "Abu Bakr Muhammad ibn Zakariya al-Razi (841-926)". Saudi Aramco World. Retrieved on 2008-01-12.
  13. ^ El Zahrawi - Father Of Surgery. Retrieved on 2007-05-04.
  14. ^ SURGERY IN ISLAM: A HISTORICAL AND CURRENT REAPPRAISAL: Lecture to second-year medical students at the Kulliyah of Medicine, International Islamic University, Kuantan on October 17, 1998 by Prof Dr Omar Hasan Kasule, Sr.. Retrieved on 2007-05-04.
  15. ^ Richard Dean Smith (1980). Avicenna and the Canon of Medicine: a millennial tribute 367-370. Retrieved on 2005-07-07.
  16. ^ Ganidagli, Suleyman M.D., Cengiz, Mustafa M.D., Aksoy, Sahin M.D., Ph.D., Verit, Ayhan M.D. (2004-01). "Approach to Painful Disorders by Serefeddin Sabuncuoglu in the Fifteenth Century Ottoman Period". Anesthesiology 100 (1): 165-169. Retrieved on 2007-05-04.
  17. ^ Pseudo-Apuleius: Papaver. Retrieved on 2007-06-15.
  18. ^ Paracelsus: the philosopher's stone made flesh. Retrieved on 2007-05-04.
  19. ^ The devil's doctor. Retrieved on 2007-05-04.
  20. ^ PARACELSUS, Five Hundred Years: Three American Exhibits. Retrieved on 2007-06-06.
  21. ^ Paracelsus: the philosopher's stone made flesh. Retrieved on 2007-05-04.
  22. ^ Stephen Harding, Lee Ann Olivier, and Olivera Jokic. Victorians' Secret: Victorian Substance Abuse. Retrieved on 2007-05-02.
  23. ^ Ole Daniel Enersen. Thomas Sydenham. Retrieved on 2007-05-02.
  24. ^ Donna Young (2007-04-15). Scientists Examine Pain Relief and Addiction. Retrieved on 2007-06-06.
  25. ^ Cite error: Invalid tag; no text was provided for refs named Zheng
  26. ^ Commissioner Jesse B. Cook (1931-06). San Francisco's Old Chinatown. Retrieved on 2007-09-22.
  27. ^ H.H. Kane, M.D. (1881-09-24). American Opium Smokers. Retrieved on 2007-09-22.
  28. ^ Opium degrading the French Navy (1913-04-27). Retrieved on 2007-09-22.
  29. ^ Alfred W. McCoy}year=1972. The politics of heroin in Southeast Asia. Retrieved on 2007-09-24.
  30. ^ {{cite web}url=http://www.drugpolicy.org/library/opium_india.cfm|title=Opium and the British Indian Empire|author=John Richards|date=2001-05-23|accessdate=2007-09-24}}
  31. ^ Commissioner Jesse B. Cook (1931-06). San Francisco's Old Chinatown. Retrieved on 2007-09-22.
  32. ^ John Rennie (2007-03-26). When a woman ruled Chinatown. Retrieved on 2007-05-12.
  33. ^ J.P. Jones (February 1931). Lascars in the port of London. Retrieved on 2007-05-12.
  34. ^ "Opium in the West." Opium Museum. 2007. Retrieved on September 21, 2007.
  35. ^ "Brilliant Chang in Limehouse." EastLondonHistory.com. Retrieved on September 21, 2007.
  36. ^ a b Alfred W.McCoy. Opium. Retrieved on 2007-06-08.
  37. ^ Wertz, Richard R. "Qing Era (1644-1912)." iBiblio. 1998. Retrieved on September 21, 2007.
  38. ^ John K. Fairbanks, "The Creation of the Treaty System' in John K. Fairbanks, ed. The Cambridge History of China vol. 10 Part 1 (Cambridge University Press, 1992) p. 213. cited in John Newsinger (1997-10). "Britain's opium wars - fact and myth about the opium trade in the East". Monthly Review.
  39. ^ Alfred W. McCoy. Opium history, 1858 to 1940. Retrieved on 2007-05-04.
  40. ^ Dikotter, Frank, Lars Laamann, and Zhou Xun Narcotic Culture: A History of Drugs in China. Co-published with C. Hurst & Co. ISBN 978-0-226-14905-9 (ISBN-10: 0-226-14905-6) Spring 2004.[1][2]
  41. ^ Lodwick, Kathleen L. Crusaders Against Opium: Protestant Missionaries in China 1874-1917 (University Press of Kentucky) Online version at Google Books [ISBN 0813119243]
  42. ^ Ellen N. La Motte. The opium monopoly. Retrieved on 2007-09-25.
  43. ^ a b Joyce A. Madancy (2004-04). The Troublesome Legacy of Commissioner Lin. Retrieved on 2007-09-25.
  44. ^ William A Callahan (2004-05-08). Historical Legacies and Non/Traditional Security: Commemorating National Humiliation Day in China. Retrieved on 2007-07-08.
  45. ^ Michael Mackey (2004-04-29). Banned in China for sex, drugs, disaffection. Retrieved on 2007-06-08.
  46. ^ Dale Gieringer (2007-03-04). State's War on Drugs - a 100-Year Bust.
  47. ^ Peter McWilliams. Ain't Nobody's Business If You Do.
  48. ^ Legal Information Access Centre. Drug laws in Australia.
  49. ^ Carstairs C. (2006). Jailed for Possession: Illegal Drug Use, Regulation, and Power in Canada, 1920-61.
  50. ^ Ryan J Huxtable and Stephen K W Schwartz, Molecular Interventions 1:189-191, 2001 [3]
  51. ^ Anthony John Carter, Narcosis and nightshade", BMJ 1996;313:1630-1632 (21 December) [4]
  52. ^ Richard Askwith, The Sunday Times (September 13, 1998). How aspirin turned hero. Retrieved on 2007-05-02.
  53. ^ Operational Medicine 2001 Field Medical Service School Student Handbook: MOLLE MEDICAL BAG/SURGICAL INSTRUMENT SET (1999-12-07). Retrieved on 2007-06-27.
  54. ^ Frick S, Kramell R, Schmidt J, Fist AJ, Kutchan TM (2005-05). "Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars". J Nat Prod 68 (5): 666-73. PMID 15921406.
  55. ^ Production of thebaine and oripavine (2004-04-20). Retrieved on 2007-05-10.
  56. ^ Meadway C, George S, Braithwaite R. (31-08-1998). "Opiate concentrations following the ingestion of poppy seed products--evidence for 'the poppy seed defence'.". Forensic Sci Int. 96 (1): 29-38. PMID 9800363. Retrieved on 2007-06-06.
  57. ^ Trafkowski J, Madea B, Musshoff F, "The significance of putative urinary markers of illicit heroin use after consumption of poppy seed products.", Ther Drug Monit 2006 Aug;28(4):552-8. PMID 16885724
  58. ^ Albert D. Fraser and David Worth (1999-10). Experience with a Urine Opiate Screening and Confirmation Cutoff of 2000 ng/ml 549-551. Retrieved on 2007-09-20.
  59. ^ Jennifer Hull (2001-06-24). Eastern Europe Shooting Up Under A Red Star. Retrieved on 2007-05-10.
  60. ^ Anil Aggrawal. Narcotic Drugs.
  61. ^ G. Shuljgin. Cultivation of opium poppy and the oil poppy in the Soviet Union.
  62. ^ W. R. Martin and H. F. Fraser (1961). "A comparative study of subjective and physiological effects of heroin and morphine administered intravenously in postaddicts". Journal of Pharmacology And Experimental Therapeutics 133 (3): 388-399. Retrieved on 2007-06-06.
  63. ^ Robinson SL, Rowbotham DJ, Smith G. (1991-07). "Morphine compared with diamorphine. A comparison of dose requirements and side-effects after hip surgery.". Anesthesia 46 (7): 538-40. PMID PMID 1862890. Retrieved on 2007-06-06.
  64. ^ Interpol.
  65. ^ UNODC World Drug Report 2005 (PDF). Retrieved on 2007-05-02.
  66. ^ Jeff Sheehy and Corinna Kaarlela (2004-01-26). Black tar heroin use explains lower HIV levels among intravenous drug users in the Western U.S.. Retrieved on 2007-05-19.
  67. ^ Alfred W. McCoy. Opium History, 1858 To 1940. Retrieved on 2007-05-04.
  68. ^ Mark Corcoran. Afghanistan: America's blind eye. Retrieved on 2007-05-11.
  69. ^ Jerry Seper (2004). U.S. set to target Afghan opium. Retrieved on 2007-05-11.
  70. ^ Rebuilding Afghanistan: Weekly Activity Update (February 24, 2005). Retrieved on 2007-05-11.
  71. ^ BBC News (2006-08-02). UN warns of soaring Afghan opium. Retrieved on 2007-06-06.
  72. ^ Jason Straziuso, Associated Press (2007-04-13). Taliban taxes opium to fund insurgency. Retrieved on 2007-06-06.
  73. ^ International Narcotics Control Strategy Report: Chemical controls. Retrieved on 2007-05-11.
  74. ^ Pablo Bartholomew (1996). Opium for the masses: photo essay on cultivation of opium in India. Retrieved on 2007-06-15.
  75. ^ Senlis Council. Feasibility Study on Opium Licensing in Afghanistan.
  76. ^ Senlis Council (2005-09-26). The Kabul International Symposium on Drug Policy. Retrieved on 2007-05-04.
  77. ^ "Poppy for Medicine: Licensing poppy for the production of essential medicines: an integrated counter-narcotics, development, and counter-insurgency model for Afghanistan." Senlis Council. June 2007. Retrieved on September 21, 2007.
  78. ^ The painkilling fields: England's opium poppies that tackle the NHS morphine crisis, Press release, 2007-15-09.
  79. ^ S. Mercadante. Oral morphine consumption in Italy and Sicily. Retrieved on 2007-05-04.
  80. ^ Benjamin Pui-Nin Mo and E. Leong Way (1966). "AN ASSESSMENT OF INHALATION AS A MODE OF ADMINISTRATION OF HEROIN BY ADDICTS". Journal of Pharmacology And Experimental Therapeutics 154 (1): 142-151. Retrieved on 2007-06-06.
  81. ^ Karl A. Sporer, M.D. (1999-04-06). "Acute Heroin Overdose" 130 (7): 584-590. Retrieved on 2007-06-11.
  82. ^ Darke S, Zador D. (1996-12}volume=91). "Fatal heroin 'overdose': a review". Addiction (12): 1765-72. PMID 8997759. Retrieved on 2007-06-11.
  83. ^ The Opium Museum.
  84. ^ Laudanum. Retrieved on 2007-05-04.
  85. ^ Mallinckrodt MSDS.
  86. ^ Anil Aggrawal. Narcotic Drugs.
  87. ^ Alfred W. McCoy. Opium History, 1858 To 1940. Retrieved on 2007-05-04.
  88. ^ Max CHAMKA; Translated by Geraldine RING. 3 grams of opium for 1 dollar. Caucaz europenews. Retrieved on 2007-05-06.
  89. ^ Finn AK and Whistler JL (2001-12-06). Endocytosis of the mu receptor reduces tolerance and a cellular hallmark of opioid withdrawal 829-39.
  90. ^ K.R. Alper, H.S. Lotsof, C.D. Kaplan (2008). "The Ibogaine Medical Subculture". J. Ethnopharmacology 115: 9-24. Retrieved on 2008-01-19.
  91. ^ Douglas Hubble (1956-02-28). Opium Addiction and English Literature. Retrieved on 2007-05-19.
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